iTIVA Anesthesia

iTIVA Anesthesia TCI simulator

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  • Country

    United States

  • Language

    English (US)

  • Last update

    March 14, 2019

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  • iTIVA Anesthesia Screenshot
  • iTIVA Anesthesia Screenshot
  • iTIVA Anesthesia Screenshot
  • iTIVA Anesthesia Screenshot

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iTIVA is a simulation program that provides information about distribution of drugs based on mathematical models, and it simulate the behavior of a TCI pump (up to 3 drugs at time), obtaining infusion rates to reach and maintain a stable target effect site concentration, those schemes can be implemented in volumetric infusion pumps, and be guided with pharmacokinetics models.
So now pharmacokinetics can become an easy topic and understanding what is going on during a infusion of a intravenous drug, too.

Pharmacokinetic models

iTIVA include 11 drugs and 40 pharmacokinetic models, that are updated continuously:

Adults: Minto
, Eleveld, Kim
Kids: Rigby-Jones, Eleveld, Ross


Adults: Shafer, Scott

Kids: Ginsberg, Encinas (Neonates)


Adults: Gepts, Bovill

Kids: Greely


Adults: Maitre

Adults: Domino, Clements-250

 Kids: Herd, Elkomy

Adults: Seifen


Adults: Dyck, Schnider


Adults: Schnider, Eleveld, Marsh, Cortinez

 Kids: Peadfusor, Kataria, Eleveld


 Adults: Hannivoort, Dyck, Lin, Venn

Kids: Potts


Adults: Albrecht, Greenblatt


Adults: Grassin-Delyle
Kids: Goobie, Grassun-Delyle

iTIVA also calculate the end tidal (Et) for Isoflurane, Sevoflurane and Desflurane for the MAC age, with the use of the Mapleson equation.

Created by David Ramirez MD, Cali - Colombia. Universidad de Valle.


iTIVA is not designed to handle intravenous drugs for individual patients. Its use is limited to educational purposes to demonstrate pharmacokinetic principles when performing intravenous anesthesia. Therefore the user assumes all risks from the use of this application for clinical purposes.
Infusion schemes are obtained from concentrations based on models published in the medical literature; therefore concentrations achieved from these schemes can vary widely, in the same manner for clinical effects.
This application should only be used by people with extensive knowledge in Anesthesiology.

We don't collect any information about you, for more info about our privacy policy, refer to

  • Keyword
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  • Density
    • keywords
    • 3
    • 6,82%
    • count, density
    • 2
    • 4,55%

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